FDA Strengthens Warning about NSAIDs Risks.

In News by Justin Welton

Click here for the FDA’s consumer update about NSAIDs. See below for PERQUE’s natural alternative to NSAIDs.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are one the most commonly prescribed drug in the United States, with millions of Americans using lower-dose OTC versions as well. They are used to treat pain from any number of ailments including headache, arthritis, postoperative pain, muscle and back ache and cancer pain.

For years, however, long-term and excessive use of NSAIDS have been associated considerable negative effects including gastrointestinal bleeding, myocardial infarction and even some cancer risk.

More recently, even short-term NSAID usage by healthy individuals has been shown to increase risk of stroke. In a study presented at the European Society of Cardiology (ESC) 2010 Congress, Dr Gunnar Gislason (Gentofte University Hospital, Hellerup, Denmark) said the results could have “massive public-health implications.”

Gislason and colleagues examined the risk of stroke and NSAID use in a population of around half a million healthy individuals living in Denmark. The researchers found that 45% of these healthy individuals had received at least one prescription for an NSAID between 1997 and 2005. They then used stroke data from further hospitalization and death registries and estimated the risk of fatal and nonfatal stroke associated with the use of NSAIDs by Cox proportional-hazard models and case-crossover analyses. The results showed that NSAID use was associated with an increased risk of stroke ranging from about 30% with ibuprofen and naproxen to 86% with diclofenac. Risk of stroke reached 90% with doses of ibuprofen over 200 mg and 100% with diclofenac doses over 100 mg showing a dose related phenomenon.

Safer, Natural Alternative

PERQUE’s Pain Guard Forte and Repair Guard have often been called “nature’s NSAIDs”. Packed with natural flavonoids and flavonols like quercetin dihydrate and orthoproanthocyanadins( OPCs), these 2 unique products offer some of the best antioxidant and inflammation support. They have excellent Oxygen Radical Absorbance Capacity (ORAC) values and gently repair at the cellular level with reducing pain and inflammation naturally. To learn more click here.

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Justin Welton
Author: Justin Welton