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PERQUE nutraceuticals are distinctive from the inside out. Each product represents a rethinking for how nutrients interact with the body and the impact they can have on the body’s ability to overcome the obstacles to repair and then stimulate natural healing responses.


Russell Jaffe, MD, Ph.D., CCN
PERQUE was founded in 1987 by Dr. Russell Jaffe (DrJ), an internal medicine physician, clinical pathologist, immunologist, and biochemist. Using the latest scientific and medical knowledge available, Dr. Jaffe has developed PERQUE, a new generation of nutritional supplements, available only through doctors and healthcare professionals.
ABOUT
PERQUE accelerates the transition from suppressing symptoms to identifying and addressing causes of ill health, thus achieving well-being for ourselves and our clients through unique integrative systems, education, innovative science, and superior products.

THE PERQUE GUARANTEE
Every PERQUE product comes with a 100%, unconditional, money-back guarantee – the strongest guarantee in the natural health industry.
Testimonials
See what our customers are saying
“I struggle with iron deficiency anemia, and the symptoms of dizziness and fatigue were affecting my daily life. Since I started using PERQUE Hematin Anemia Guard™, I’ve noticed a significant improvement. The supplement is gentle on my stomach, and its 100% bioavailable formula means I’m absorbing the nutrients I need. Within a few weeks, I felt more energized and alert, and the dizziness has subsided. I highly recommend it to anyone dealing with similar challenges!”
Customer from Culpeper, VA
“I was looking for a way to improve my health when I learned about to PERQUE EPA/DHA Guard™. After incorporating it into my daily routine, I noticed an improvement in my blood work, especially a significant increase in my good cholesterol (HDL) levels. This positive change gave me the motivation to stay consistent with it. It is now part of my daily routine. I recommend it to anyone seeking a natural way to support their cholesterol levels and overall health.”
EB from Culpeper, VA
“I’ve used the PERQUE Energized Double Zinc Guard™ for the past 10 years. This has been one of the most effective products to help me keep my zinc level balanced. At first, I kept a bottle on hand during the fall and winter seasons, but it’s become a year-round supplement for me. Definitely recommended!!”
PERQUE Customer, Concord, VA
“I started PERQUE Choline Citrate™ and PERQUE Mg Plus Guard™ and was pleasantly surprised with the improved mental clarity and increased motivation within a very short two days but was also quite happy to find that I had not had any more muscle cramps. I am excited to start offering these products to my patients as well.”
Susan M. Eichorst, PA-C, MMSc
Littleton, CO
“Thanks to the PERQUE products Mito Guard Plus, D3 Cell Guard, Double Zinc Guard and Activated B12 Guard, my post-COVID fatigue has practically disappeared. In fact, I began to notice improvement within a couple of weeks. The fatigue as we hear about it in the news takes much longer to disappear in other people than the three months I suffered from it. That’s very much thanks to you!”
A.S.
Entrepreneur, UK
“The purity and quality of the supplements are often really important, in that patients who can’t tolerate other things can often tolerate the PERQUE products. PERQUE Potent C Guard™ is unlike anything else that’s out there.”
N Schwartz, MD
Mequon, WI
“I have had direct experience with PERQUE products. In 24 hours, these products accomplished what other products failed to do in 6 weeks; they completely relieved all of my bronchial symptoms.”
Douglas Fleckman, CCN, FACN
AR
“We have wonderful, wonderful results with PERQUE products. I love PERQUE Repair Guard™. I’ve had about nine people with torn rotator cuffs, my brother being the first one, and eight out of nine — no surgery necessary.”
G.F. Mauer, RPh, CCN
Brazil, IN
“I have had some pretty intense nausea at times and I’ve taken the PERQUE DigestiveAide™ and it has worked like a miracle. Within 15 minutes of taking it, the nausea is gone. I took it this morning and the nausea stayed gone until my next dose. Great for someone like me who has digestive issues.”
P. Jones
Haymarket VA
“My joints say ‘thank you’ as I believe it is the best supplement on the market to maintain and restore joint cartilage.”
Dr. Ron Elin
Louisville, KY
“I tried the PERQUE Adreno Distress Guard™ sample and wowzah – great energy ALL day long!”
A Functional Medicine Family Nurse Practitioner
Bend, OR
“I love PERQUE Potent C Guard™! Ever since I started taking it regularly a few years ago, my skin and acne have become so much better. I also haven’t had bad dry skin or itching in the winter time.”
V Mason, Grad Student
London, UK